Chemicals are considered highly toxic when the Volume (e.g., liter (L)) of medium (i.e., air or water) the organism LC 50 is often expressed as mg of chemical per
Milligrams (mg) of chemical per kilogram (kg) of body LD 50 is generally expressed as the dose in Lethal concentration (LC 50) that causes death (resultingįrom a single or limited exposure) in 50 percent of the treatedĪnimals. Measure of acute toxicity is the lethal dose (LD 50) or On Toxicity Classification and LD 50/LC 50. Oral LD 50 in rats is greater than 4320 mg/kg. Glyphosate is low in toxicity to rats when ingested.However, this hypothesis has been disputed. The mechanism of toxicity of glyphosate in mammals is unknown,īut it may cause uncoupling of oxidative phosphorylation.Used in some commercial glyphosate-based formulations, may be more toxic by the oral route to animals than glyphosate Studies indicate that the surfactant polyoxyethyleneamine or polyethoxylated tallow amine (both abbreviated POEA),.The absence of this pathway in mammals mayĮxplain the low toxicity of glyphosate to non-target organisms. The shikimic acid pathway is specific to plants and some microorganisms.The sodium salt of glyphosate can act as a plant growth regulator and accelerate ripening of specific crops.Death of the plant may take from 4 to 20 days to occur.
select your state then click on the link for "State Products." To find a list of products containing glyphosate which are registered in your state, visit the website.The NPIC fact sheets on Signal Words and Inert or "Other" Ingredients. See the pesticide label on the product and refer to Toxicity of the active ingredient and other ingredients in the product. Signal words for products containing glyphosate may range from Caution to Danger.Always read and follow the label when applying pesticide Uses for individual products containing glyphosate vary widely.4,9 This fact sheet does not address glyphosate-tolerant crops. Glyphosate-tolerant soybeans, corn, cotton,Īnd canola are examples of such plants. Some plants have been genetically engineered to be resistant to glyphosate.Sites with the largest glyphosate use include soybeans, field corn, pasture and Glyphosate is one of the most widely used herbicides with applications in agriculture,įorestry, industrial weed control, lawn, garden, and aquatic environments.2,7 Physical / Chemical Properties: Glyphosate and associated forms Of these, the isopropylamine salt is mostĬommonly used in formulated products. Technical grade glyphosate is used in formulated products, as are the isopropylamine,.1,2,4 Unless otherwise stated, all data in this fact sheet refer to the acid Salt, isopropylamine salt, potassium salt, sodium salt, and trimethylsulfonium or trimesium Formulations of glyphosate include an acid, monoammonium salt, diammonium.6 See the text box on Laboratory Testing. In 1974 5, and reregistration was completed in 1993. Registered for use by the United States Environmental Protection Agency (U.S. Glyphosate's potential as an herbicide was reported in 1971.Glycine 3 and the Chemical Abstracts Service (CAS) registry number 1 The International Union of Pure and AppliedĬhemistry (IUPAC) name for glyphosate is N-(phosphonomethyl) 1 When used in smaller quantities, glyphosateĬan act as a plant growth regulator. Glyphosate is a non-selective systemic herbicide that is appliedĭirectly to plant foliage.